Characterization of RNA damage under oxidative stress in Escherichia coli
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چکیده
منابع مشابه
Ubiquinone limits oxidative stress in Escherichia coli.
Ubiquinone is an essential redox component of the aerobic respiratory chains of bacteria and mitochondria. It is well established that mammalian ubiquinone can function in its reduced form (ubiquinol) as a lipid-soluble antioxidant preventing lipid peroxidation. The objective of this study was to test the hypothesis that prokaryotic ubiquinone is involved in the defence against oxidative stress...
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In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance of fragmented chromosomes and a decrease in terminus concentration, leading to a dramatic increas...
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ژورنال
عنوان ژورنال: Biological Chemistry
سال: 2012
ISSN: 1437-4315,1431-6730
DOI: 10.1515/hsz-2011-0247